Pantoprazole 40 MG
Domperidone 30 MG

Therapeutic Class

GIT Regulators & Anti-Inflammatories ,  Antacids, Antireflux Agents & Antiulcerants ,  Antiemetics

Uses and Benefits

Panby-D Capsule is used to treat gastro-oesophageal reflux disease, peptic ulcer, H. Pylori infection, prophylaxis of NSAID induced ulcers, zollinger-ellison syndrome, erosive oesophagitis. It is also used to treat dyspepsia, heart burn, epigastric pain, nausea and vomiting. However, the uses mentioned here are not exhaustive. There may be other conditions for which this medication may be used upon doctor’s discretion.

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Mechanism of Action of Drugs- Pantoprazole is a proton pump inhibitor which acts by inhibiting the gastric acid secretion in the stomach.
Domperidone possesses anti-emetic properties which help reduce vomiting and vomiting sensation; and also treats gastric problems to an extent.

Contraindications and Caution

Patients with the following conditions are suggested to seek advice from their health care professional before taking the Panby-D  Capsule:

  • Hypersensitivity to any of the ingredients used in the Panby-D Capsule such as Pantoprazole and Domperidone
  • QT prolongation
  • Electrolyte disturbance
  • Cardiac disease
  • GI haemorrhage
  • Hepatic impairment, moderate to severe
  • Caution:
  • Long term use
  • High dose
  • Hypomagnesemia
  • Patients 50 years and older

Side and Adverse Effects

The following side effects may or may not occur during the usage of Panby-D Capsule. It is generally well tolerated when taken in the prescribed dosage guidelines. More common ones are generally mild and may include:

  • Headache
  • Diarrhea
  • Thrombophlebitis
  • Abdominal pain
  • Nausea/Vomiting
  • URI sx
  • Fever
  • Rash
  • Dizziness
  • Flatulence
  • Arthralgia
  • Vitamin B12 Deficiency
  • Fundic gland polyps
  • Dryness of mouth
  • Increased prolactin levels
  • Amenorrhea
  • Gynaecomastia
  • Best pain and tenderness
  • Urticaria
  • Rash
  • Pruritus
  • Transient intestinal cramps
  • Diarrhea
  • Nervousness
  • Anxiety
  • Arrhythmias
  • Bradycardia
  • Tachycardia


Rare but more serious adverse effects may include:

  • Hypersensitivity reaction
  • Anaphylaxis
  • Erythema multiforme
  • Stevens-johnson syndrome
  • Toxic epidermal necrolysis
  • Interstitial nephritis
  • Renal impairment
  • Pancreatitis
  • Rhabdomyolysis
  • Fractures
  • Hyponatremia
  • Hypomagnesemia
  • Lupus erythematosus
  • C. Difficile associated diarrhea
  • Blood dyscrasias
  • Hepatic impairment
  • Serious ventricular arrhythmia
  • Sudden cardiac death
  • Torsade de pointes
  • Anaphylaxis
  • Angioedema

How to Use

Do not exceed the dose prescribed by your doctor. Swallow the Panby-D  Capsule, immediately after opening the Capsule from the strip. Do not break/crush/ chew the capsule.

Avoid missing or forgetting a dose. If you do, take it as soon as you remember; but if it is almost time for your next dose, skip it and take it according to your normal schedule. Don’t consume two doses at the same time which is dangerous to your health.

Panby-D Capsule may be taken 15-30 min before food or take it on an empty stomach.
Take the medicine twice or thrice in a day or as recommended by your doctor.
Panby-D Capsule is not recommended in children younger than 5 years.


Avoid taking more than the prescribed dosage. In case of an accidental overdose, promptly seek medical advice. Depending on the dosage, symptoms may vary but you may experience one or more of the following signs or symptoms:

  • Altered consciousness
  • Convulsion
  • Agitation
  • Somnolence
  • Extrapyramidal reactions
  • Disorientation

Warnings and Precautions: Take Panby-D  Capsule only on the advice of a medical practitioner. Dosage adjustment or complete avoidance of the medication may be required in the following conditions:

Pregnancy: Safety not established. Therefore, inform your doctor if you are pregnant or planning to get pregnant during treatment.

Lactation: Inform your doctor if you are a nursing mother because safety during lactation is not yet established.

Drug Interactions: Inform your doctor if you are on any medication such as Digoxin, methotrexate, diuretic or water pill, Ketoconazole, erythromycin, opiod analgesics and Muscarinics.


  • Keep the medicine out of sight and reach of children.
  • Store at room temperature away from heat and moisture.
  • Do not use the medicine beyond its expiry.
  • Do not accept the torn strip or a broken Capsule.

FDA Pregnancy Category

Category N: No information available.